Chains, dimers, and sandwiches: melting behavior of DNA nanoassemblies.
Identifieur interne : 002F19 ( Main/Exploration ); précédent : 002F18; suivant : 002F20Chains, dimers, and sandwiches: melting behavior of DNA nanoassemblies.
Auteurs : J. Bayer [Allemagne] ; J O R Dler ; R. BlosseySource :
- Nano letters [ 1530-6984 ] ; 2005.
Descripteurs français
- KwdFr :
- ADN (), ADN (analyse), ADN (ultrastructure), Conformation d'acide nucléique, Cristallisation (), Dimérisation, Modèles chimiques, Modèles moléculaires, Nanostructures (), Nanostructures (analyse), Nanostructures (ultrastructure), Oligonucléotides (), Oligonucléotides (analyse), Simulation numérique, Solutions, Structures macromoléculaires (), Structures macromoléculaires (analyse), Température de transition, Test de matériaux.
- MESH :
- analyse : ADN, Nanostructures, Oligonucléotides, Structures macromoléculaires.
- ADN, Conformation d'acide nucléique, Cristallisation, Dimérisation, Modèles chimiques, Modèles moléculaires, Nanostructures, Oligonucléotides, Simulation numérique, Solutions, Structures macromoléculaires, Température de transition, Test de matériaux.
English descriptors
- KwdEn :
- Computer Simulation, Crystallization (methods), DNA (analysis), DNA (chemistry), DNA (ultrastructure), Dimerization, Macromolecular Substances (analysis), Macromolecular Substances (chemistry), Materials Testing, Models, Chemical, Models, Molecular, Nanostructures (analysis), Nanostructures (chemistry), Nanostructures (ultrastructure), Nucleic Acid Conformation, Oligonucleotides (analysis), Oligonucleotides (chemistry), Solutions, Transition Temperature.
- MESH :
- chemical , analysis : DNA, Macromolecular Substances, Oligonucleotides.
- chemical , chemistry : DNA, Macromolecular Substances, Oligonucleotides.
- analysis : Nanostructures.
- chemistry : Nanostructures.
- methods : Crystallization.
- chemical , ultrastructure : DNA, Nanostructures.
- Computer Simulation, Dimerization, Materials Testing, Models, Chemical, Models, Molecular, Nucleic Acid Conformation, Solutions, Transition Temperature.
Abstract
We have studied, in experiment and theory, the melting behavior of DNA nanoassemblies of perylenediimide-bis-oligonucleotides (PON), in which two short oligonucleotide chains (16- or 24-mers) are attached to the extremities of a spacer molecule. By varying both the sequence orientation (exchange of 3' and 5' ends neighboring the spacer) and the oligomer composition of the solutions, nanoassemblies of different complexity can be generated. Our results show a subtle dependence of the melting behavior on the supramolecular arrangement of the DNA-based assemblies.
DOI: 10.1021/nl0478631
PubMed: 15755101
Affiliations:
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Le document en format XML
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<term>Modèles moléculaires</term>
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<front><div type="abstract" xml:lang="en">We have studied, in experiment and theory, the melting behavior of DNA nanoassemblies of perylenediimide-bis-oligonucleotides (PON), in which two short oligonucleotide chains (16- or 24-mers) are attached to the extremities of a spacer molecule. By varying both the sequence orientation (exchange of 3' and 5' ends neighboring the spacer) and the oligomer composition of the solutions, nanoassemblies of different complexity can be generated. Our results show a subtle dependence of the melting behavior on the supramolecular arrangement of the DNA-based assemblies.</div>
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